CeeDee Lamb could have one of his biggest games playing against a Lions defense that's tougher against the run than the pass.
The Saints are tougher on the boundary than in the slot, which should provoke a big game from Amon-Ra St. Brown.
The Indianapolis secondary is weakest on the boundary and downfield, where Mike Evans is at his best.
Juan Carlos Blanco surveys the extremely busy Week 11 Sunday morning injury landscape and dishes the latest news on the potential availability of multiple big fantasy names.
It's already been a brutal week for injuries, and now Tyler Lockett is in danger of missing a game for the first time this season.
Playing at home and against the Bears, the Week 11 setup couldn't be much easier for Amon-Ra St. Brown.
Aaron Jones finally got back to a high-usage role after nearly two months of being held back by a hamstring injury.
Chuba Hubbard dominated Carolina's backfield work even with Miles Sanders back in the lineup, and Denver's Javonte Williams returned to a workhorse role against the Chiefs.
A.J. Brown and DeVonta Smith are glaring mismatches against the Dolphins corners, setting the stage for a runaway shootout.
The Vikings face a simple reality Sunday: either Jordan Addison has a strong game, or the Minnesota passing game falls apart.
It might be now or never for DeAndre Hopkins, who catches the Colts battered and weak at cornerback.
The Dolphins are looking to bring a shootout to the Bills, but Stefon Diggs is prepared to shoot back against Miami's questionable pass defense.
Jerry Donabedian scours Friday injury reports for anything that might impact games Sunday and Monday, with potential Week 3 game-time decisions including Jaylen Waddle, Joe Burrow and Aaron Jones.
The Colts' cornerback personnel is weak but their run defense is strong, setting up a feast for Calvin Ridley and the Jags passing game.
Amon-Ra St. Brown and the Lions receivers project for a substantial advantage against the Chicago secondary.